COVID-19 Perceptions and Reality


COVID-19 Perceptions and Reality

This part of our blog, or information share is part of study material and training HSE-RM solution has provided, its tough to reach out to the masses, some might agree and disagree on practices. HSE-RM Solution has always tried to be innovative and expressive in terms of saying “The Why Spend Theory”. We prefer to adopt best ones, always remember “TO LEARN SOMETHING ITS IMPORTANT TO UNLEARN FIRST”
I came across an article published I remember reading which said about the question everyone wants to know an answer for: “When people ask, ‘When will this end?’ they are asking about the social ending,” said Dr. Jeremy Greene, a historian of medicine at Johns Hopkins.

In other words, an end can occur not because a disease has been vanquished but because people grow tired of panic mode and learn to live with a disease.

Searches everyday say “Coronavirus (COVID-19) events as they happen” do really need to read all this.

Let’s understand the basics first and understand the depths of it. Few recent terms used are first to be realised.
ð        Pandemic: A pandemic is declared when a new disease for which people do not have immunity spreads around the world beyond expectations.
ð        Epidemic: An epidemic is a large outbreak, one that spreads among a population or region. It is less severe than pandemic due to a limited area of spread.
ð        Endemic: A disease is called endemic when the presence or usual prevalence of its infectious agent is constant within a given geographical area or population group.

How to clean and disinfect? big question asked, and panic buy, opportunity and business are flourishing. New vendors came in market suppling products, like Fumigators, Sanitizer tunnel, hand sanitizers, mask, gloves, PPE Kit and what not. To everyone’s surprise everyone is selling, and demand is increasing every day. Most of the people didn’t even thought of why buy its precaution take it or this will happen or that will happen, and fear did its part in making opportunist market.  “TRUE” but fact.

Let us argue case against each product basic which are in high demand.
1.     Mask
·         Did we see the guideline, who needs to ware mask [person who has cold, cough so that when he sneezes, or cough droplet spread does not happen]?
·         Now normal person to protect himself as all will not listen started wearing mask and demand increased.
·         Which type of mask to wear? Very simple any type any which will not let the droplet to come out. It can be homemade with 3-4 layer of cloth as well. (NO need for common people to wear N95)  
·         Mask with face shield: super good idea, but who is intentionally going to spit on you? Why you need the product for style good actual use not known along with its efficiency.
·         Another major question was on re-use of mask 80% of the mask are single use only, other then homemade cloth mask which can be washed and re-used.
2.     Sanitizer Tunnel:
·         The concept of Sanitizer tunnel is not new, most of pharma people are already aware of air washer and fumigation technology. But its good for area where the fumigant is going to reside over the surface after 10-15 min. of treatment. [without human presence]
·         Question is on effectiveness understanding before purchase, what are you trying to do, most of the tunnels use disinfectant spray [refer MSDS direct ingestion/exposure to eyes it is an irritant and requires medical attention] as per MSDS of disinfectants soap solutions or any chemical intake is not good by any means unless person is properly suited with CBRN (chemical, biological, radiological and nuclear suit) used for chemical rescue with self-contained breathing apparatus (SCBA) set.
·         Also medically these tunnel what is quality test to assurance that its effective and for how long person has to stay inside. [if person stays longer inside risk of chemical exposure & health hazard persist and for less exposure disinfectant is of no use.] how to verify this is simple take swab test sent it to lab for bacterial count some of places we got the test done and result was its not at all effective.
·         Sanitizer tunnel was then converted to Steam tunnel, it was advised to use steamer for better health. Normally advised by ENT (Ear Nose Throat) Doctors also to take plain steam.
3.     Gloves
·         Gloves are made for single use only especially surgical ones for they come in sterilized packing, once used its of no use.
·         People are using cotton gloves, it will attract bacteria and dirt so what is the use, its important to understand use of glove. Where we should use glove, only where there is possibility that multiple people have toughed and you are not going to get a chance to wash sooner.
·         More then gloves if we follow hand hygiene its better washing hands. If possible avoid contact to surface.
4.     Hand Sanitizer
·         Hand sanitizers are more dangerous for industry, for many people work near moving parts there is possibility of static and also surface temperature can be auto ignite for sanitizer as well.
·         Few incidents also came out typically sanitizer in car and there was fire, labour burning hand due to spark by contact of surface with high temperature.
·         Sanitizers are good to be used over glove not on hands, if there is possibility of washing hands avoid use of hand sanitizer (remember its chemical also) larger exposure may cause harm to dermal skin layers.
·         We should consider hand sanitizer as SOS/emergency only, facilities have started putting it everywhere but use and effect were not analysed properly.
·         Again, remember contact surface, wash your hands with soap if not possible and its unavoidable you have to touch surface you can use Hand Sanitizer.
5.     PPE Kits
·         Most of the kits I have seen are single use only, but its for Medical staff, not for industry, why we are on panic mode so much. Its like my opening statement that people want to live with the disease then its fine.
·         I would suggest start giving this kit to CORONA patient contain them.
·         In Pharma there is over gowning procedure same if required can be adopted for industry as well, but only selective where occupancy is high and in close proximity there are many people.
·         These are last resort if above cannot be done.

SESSION: SOLUTIONS
-       Hand Hygiene
o    Maintain proper Hand always wash hand prior to eating.
o    Avoid touching your face when you are working.
o    Before touching surface, you can use disinfectant to wipe it. [Surface disinfectants are many in market use any or you can prepare soap solution] only on surface where other person has touched as well.
o    Washing hands for 20 seconds is not enough properly washing hand is required. Use proper method follow teach and guide for the same. [Training to be Given] Refresher training to be given to people, engage them and family prepare about hand hygiene.]
Hands are main source on contacting any contamination. Our first contact to any surface is hand. As best practice we always force people to follow hand hygiene. Below video link is to explain importance of it.


-       Sanitization:
o    Sanitization has two parts
§  Personal and
§  Surrounding Surfaces.
o    Personal
§  Personal Sanitization include our behaviour, how we work, what type of work we have.
§  Personal Hygiene is one of the major concerns among many people. Its one of the reasons for the spread of any diseases. 
§  Personal Hygiene is not limited to one keeping self-clean, but how we behave what are our practices when we work, manners etc. [Most focused area]
§  Personal hygiene basic chart includes below things that most of us are aware
§  Part of BBS (behaviour base safety)]
ð        Sleep
o    Early to bed, early to rise. [Is known to all]
o    Minimum 6-8hr of sleep is said to be completely rested.
ð        Teeth
o    Brush teeth every morning and night. [most of us follow morning routine but forget in night]
o    Teeth are one of major source of providing host to any bacteria or virus, for food is there which can decay and can help it grow.
ð        Nails
o    Trim nails weekly, keep nails short and clean.
o    Dirt below nail can enter through ingestion when we eat with hand.
o    Most people have habit of eating with hand without ensuring proper hand cleaning and shorter nails hence avoid eating with hand try spoon.
o    Basic Manner eating with spoon and how to avoid hand getting dirty
ð        Hair
o    Wash your hairs often keep it neat. [Washing hair is needed for most of the time we touch our hairs]
o    Hairs have natural static to attract dirt and dust (source of bacteria and Virus) if hairs are not clean and we touch them contamination can spread.
o    Full bath should include washing hair every day, especially when we come from outside/Work. Makes you feel better and fresh as well.
ð        Exercise
o    Physical exercise is very important, only yoga sitting in one place wont work.
o    Physical exercise does not mean your work or daily household work.
o    Everyday minimum 10-15 min walk, jump, run, skipping etc. anything that exerts our body.
o    Physically these 10-15 min workouts will help you increase your stamina and breathing. (For better Immune system)
ð        Hygiene
o    Bath or Shower and change personal garments daily, wash hands after visiting toilet and before eating.
o    Most people avoid taking full bath when they return home from work this is bad hygiene, you must.
o    Also, at work, personal hygiene is must washing hands before eating, cleaning them before using your electronics (Personal phones).
o    Communication system used at offices should be speaker based if possible, if unavoidable try using hands free system

§  Explaining use of electronics in Personal hygiene
·         While picking up phone if you feel your ands are dirty try simple device like hands free on auto answer mode.
·         Mobile phones are most venerable source of contamination try and avoid use in public. Also, at work if extremely necessary try touch pencil with cover or put a plastic cover over your phone and then touch.
o    Procedure will be washing hands with clean hands take a Ziplock bag/ cover bag mostly used during rains. now while removing cover also first clean the surface where you want to place your phone, remove cover don’t touch it and wash your hands now you are ready to go try not to do it in work premises its better you do it at home.  
o    At home always have a dedicated place for keeping mobile phones away from bedroom (have fix time schedule of phone at home, give time to family)
o    As part of personal hygiene its must to ensure anything that we get from outside is cleaned first, as soon we are back home first try not to touch any surface but wash your hands, change clothes (if you were been to a place of public access, workplace, shops, malls, bus stand, or any public place)  
§  Surrounding Surfaces
·         Surface sanitization is most easy to understand and follow, guidelines clearly states contact surfaces only, we try and overdo by spraying the entire facility.
·         In panic people are sanitizing entire factory premises, containers, dispatch vehicles etc. few incidents that came across was self-ignition material burned, person injury due to spillage, fumes causing harm etc.
·         Surface sanitation should be done with normal disinfectant only most of the surfaces to be covered with wipeable coating covers so that disinfectant can be used, specially workstations. Files, stationary to be touched by one-person at a time only ensuring he has washed hand before touching them.




SESSION : BASICS OF UNDERSTANDING VIRUS & BACTERIA
How do viruses differ from bacteria?
By Definition:
Viruses are tinier than bacteria. In fact, the largest virus is smaller than the smallest bacterium. All viruses have is a protein coat and a core of genetic material, either RNA or DNA. Unlike bacteria, viruses can't survive without a host. They can only reproduce by attaching themselves to cells. In most cases, they reprogram the cells to make new viruses until the cells burst and die. In other cases, they turn normal cells into malignant or cancerous cells.

S.N.
Character
Bacteria
Virus
1
Cell type
Prokaryotic cells
Acellular
2
Number of cells
Single-celled
No cell
3
Size
Larger than viruses (0.3-2 μ)
Minute (0.02-0.3 μ)
4
Microscopy
Visible under Light Microscope.
Visible only under an Electron Microscope.
5
Shape
Common bacterial cell shapes include
ð         cocci (spherical),
ð         bacilli (rod-shaped),
ð         spiral, and
ð         vibrio (comma-shaped).
Viruses typically have
ð         spherical (polyhedral),
ð         rod-shaped, or
ð         helically shaped capsids
ð         while some viruses, such as bacteriophages, have complex shapes.
6
Cellular Machinery
Possesses a cellular machinery 
Lack of cellular machinery
7
Type of organism
Mostly intercellular organisms (i.e. they live in-between cells); some intracellular.
Intracellular organisms (they infiltrate the host cell and live inside the cell). 
8
Structure
Organelles and genetic material within a cell wall
Genetic material within a capsid, some have an envelope membrane.
9
Cell wall
Cell wall made of peptidoglycan and lipopolysaccharide.
No cell wall. Protein coat presents instead.
10
Cellular membrane
Cell membranes present. No sterol except in Mycoplasma cells which have cholesterol.
Some are enveloped, but no membrane function.
11
Genome
DNA and RNA
DNA or RNA
1 chromosome
1 nucleocapsid except in segmented or diploid viruses
No histones

12
Nucleic acid
DNA and RNA floating freely in the cytoplasm.
DNA or RNA is enclosed inside a coat of protein.
13
mRNA
Mono- and poly-cistronic mRNA
Some have poly-cistronic mRNA and post-translational cleavage.
14
Cell organelles
Presence of non-membrane bound cell organelles.
Absent. Uses host organelles; obligate intracellular parasites
15
Ribosomes
70s ribosomes (30s+50s)
No ribosomes
16
Living attributes
Living organisms.
Between living and non-living things.
17
Replication
Binary fission (asexual). DNA replicates cells continuously.
It invades a host cell and takes over the cell causing it to make copies of the viral DNA/RNA. Destroys the host cell releasing new viruses.
18
The need for host cell
Able to reproduce by itself.
Need a living cell to reproduce
19
Other forms
In some spore-forming bacteria, sporulating forms can be seen.
Besides viruses, two other acellular forms exist Viroids and Prions.
20
Cells Infected
Animal, Plant, Fungi
Animal, Plant, Protozoa, Fungi, Bacteria, Archaea
21
Infection
Localized
Systemic 
22
Induction of Fever
A bacterial illness notoriously causes a fever
A viral infection may or may not cause a fever.
23
Duration of illness
A bacterial illness commonly will last longer than 10 days.
Most viral illnesses last 2 to 10 days.
24
Diseases/Infections
Food poisoning, gastritis, and ulcers, meningitis, pneumonia, etc
AIDS, common cold, influenza, chickenpox, etc
25
Susceptibility to Antibiotics
Most bacteria are susceptible to antibiotics.
The virus does not respond to antibiotics.
26
Treatment
Antibiotics
Antiviral drugs
27
Beneficial use
Some bacteria are beneficial (as normal flora, probiotics, fermenters, etc.)
Viruses are not beneficial. However, a particular virus may be able to destroy brain tumors. Viruses can be useful in genetic engineering.
28
Examples
E.coliSalmonella spp., Listeria spp., Mycobacteria spp., Staphylococcus spp.Bacillus anthracis, etc.
HIV, Hepatitis A virus, Rhino Virus, Ebola virus, etc. now CORONA as well.
SESSION : SOURCE OF INFORMATION
India and Known Source of Information
The National Institute of Virology is one of the major Institutes of the Indian Council of Medical Research (ICMR). It was established at Pune, Maharashtra, India in 1952 as Virus Research Centre (VRC) under the auspices of the ICMR and the Rockefeller Foundation (RF), USA. It was an outcome of the global programme of the RF for investigating the Arthropod Borne viruses. Since the studies on arboviruses and their arthropod vectors involve most of the basic principles and techniques of general virology, entomology and zoology, these viruses were also considered to be an ideal group, to begin with, for intensive training and research in virology. The RF withdrew its support in 1967 and since then the institute has been funded by the ICMR.

The institute was designated as one of the collaborating laboratories of the World Health Organization (WHO) in 1967 and it started functioning as the regional centre of the WHO for South-East Asia for arbovirus studies from 1969. Since 1974, it has been functioning as a WHO collaborating centre for arbovirus reference and research. In 1995 it has been redesignated as the WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research and Rapid Diagnosis of Viral Diseases.

NIV is also the National Centre for Hepatitis and Influenza. The field unit of NIV at Bengaluru is one of the centres under National Polio Surveillance Programme conducting surveillance of acute flaccid paralysis cases from Karnataka as a part of Global Polio Eradication Programme of the WHO South-East Asia region since 1997. World Health Organization (WHO) Regional Collaborating Centre for Reference and Research on Arboviruses, Influenza and Measles as well as National Reference Centre for Hepatitis, Avian Influenza and emerging infectious diseases.

ICMR Guidelines

COVID-19: Guidelines on disinfection of common public places including offices

Scope: This document aims to provide interim guidance about the environmental cleaning /decontamination of common public places including offices in areas reporting COVID-19.

Coronavirus Disease 2019 (COVID -19) is an acute respiratory disease caused by a novel Coronavirus (SARS-CoV-2), transmitted in most instances through respiratory droplets, direct contact with cases and also through contaminated surfaces/objects. Though the virus survives on environmental surfaces for varied period of time, it gets easily inactivated by
chemical disinfectants.

In view of the above, the following guidelines are to be followed, especially in areas reporting COVID-19. For ease of implementation the guideline divided these areas into (i) indoor areas, (ii) outdoor areas and (iii) public toilets.

Office spaces, including conference rooms should be cleaned every evening after office hours or early in the morning before the rooms are occupied. If contact surface is visibly dirty, it should be cleaned with soap and water prior to disinfection. Prior to cleaning, the worker should wear disposable rubber boots, gloves (heavy duty), and a triple layer mask.
[Remark: As stated all above we were already doing, What we should understand is that we need to ensure its done. Guidelines specifies to clean contact surfaces surface, also it states to discard PPE not to be reused.]
Outdoor areas
Outdoor areas have less risk then indoor areas due to air currents and exposure to sunlight. These include bus stops, railway platforms, parks, roads, etc. Cleaning and disinfection efforts should be targeted to frequently touched / contaminated surfaces as already detailed above.
·     To prevent cross contamination, discard cleaning material made of cloth (mop and wiping cloth) in appropriate bags after cleaning and disinfecting. Wear new pair of gloves and fasten the bag.
·     Disinfect all cleaning equipment after use and before using in other area
·     Disinfect buckets by soaking in bleach solution or rinse in hot water
Information on initiatives
Box 1.1. Global and national initiatives for infection prevention and control
Global action
·     International Health Regulations, 2005
o    containment of AMR, a strategic priority
·     United Nations Sustainable Development Goals
o    emphasis on safe water, sanitation and hygiene (WASH)
·     World Alliance for Patient Safety
·     WHO Patient Safety Programme
o    “clean care is safer care”
·     Regional Strategy for Patient Safety (2016–2025), WHO South-East Asia Region
·     WHO Guidelines on Core Components of Infection Control Programmes
National initiatives
·     Biomedical Waste Management Rules in 1998 (revised in 2016 and 2018) by Ministry of Environment and Forests
·     The “Kayakalp” programme by the Government of India, 2015
·     National Guidelines on Clean Hospitals (Swacchhta Guidelines), 2015
·     National Quality Assurance Standards for Public Health Facilities, 2017
·     National Patient Safety Implementation Framework, 2018–2025

Annex 2: IPC precautions pending confirmation of diagnosis

Clinical Syndrome or Condition
Suspected Pathogen
Empirical precautions (always includes standard Precautions)
Cough/ fever/ pulmonary infiltrate in any lung location in a patient with a history of recent travel (10–21 days) to countries with active outbreaks of SARS, avian influenza
Severe acute respiratory syndrome virus (SARSCoV), avian influenza,
novel coronavirus, M. tuberculosis
Airborne plus contact precautions plus eye protection; droplet precautions instead of airborne precautions if tuberculosis unlikely


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